By Syed Z. Ali MD, Yener S. Erozan MD, Ralph H. Hruban MD
Medical and radiologic examinations can't reliably distinguish benign or inflammatory pancreatic sickness from carcinoma. The elevated use of pancreatic effective needle aspiration (FNA) in addition to advances in imaging thoughts and the creation of endoscopic ultrasound assistance have resulted in much better detection and popularity of pancreatic plenty. hence, pancreatic cytopathology is imperative to exact pre-operative prognosis but it's a difficult diagnostic zone with numerous power pitfalls and "look-alike" lesions. Skillful reputation and an wisdom of the restrictions of the process are crucial in heading off misdiagnosis of those harmful lesions.
Atlas of Pancreatic Cytopathology with Histopathologic Correlations fills a void in present pathology literature. With 450 high-resolution pictures, together with photographs of histopathologic and radiologic good points, this functional atlas provides an built-in method of diagnostic cytopathology that may aid surgeon cytopathologists, cytotechnologists, and pathologists keep away from power pitfalls and "look-alike" lesions. Written via well-known specialists within the box, the large high-resolution colour pictures of the attribute beneficial properties of pancreatic illness are offered with targeted descriptions that disguise vintage positive aspects, diagnostic clues, and capability pitfalls.
Atlas of Pancreatic Cytopathology with Histopathologic Correlations is a priceless source for the professional cytopathologist, normal and surgical pathologists, pathology trainees, and cytotechnologists.
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Additional resources for Atlas of Pancreatic Cytopathology: With Histopathologic Correlations
Reproduced with permission from AJR 2002:179; 725–730. Sheth S, Hruban RH and Fishman EK. ) (B) Venous phase contrast-enhanced axial CT of the upper abdomen demonstrates the lesion, but the changes are more subtle because the difference in enhancement between the normal pancreas and the mass is less. Chapter 2: Radiologic Characteristics of Pancreatic Disease 23 Selected Cases Illustrating Salient Radiologic Characteristics Case 8 Small pancreatic endocrine neoplasm (45-year-old man with history of non insulin dependent diabetes).
This appearance is nonspecific, particularly if no other cellular component is identified. Chronic pancreatitis should be considered in the differential diagnosis, as well as sampling of a peripancreatic lymph node. Radiologic correlation would help to establish the diagnosis. 30 — Lymphoepithelial cyst. The characteristic admixture of benign squamous cells in a lymphocytic background is seen. The squamous cells appear mature and normal. Squamous cells in a pancreatic FNA raise a differential diagnosis of squamous cell contamination from the tubular esophagus (in EUSguided aspirates), epidermoid cyst, dermoid cyst, primary adenosquamous and metastatic squamous cell carcinoma.
Imaging findings associated with vascular encase- Atlas of Pancreatic Cytopathology ment include loss of the fat planes surrounding the celiac axis, hepatic artery, and superior mesenteric artery with soft tissue growing along, and sometimes narrowing, these critical vessels. Adenocarcinoma may also significantly narrow or occlude the portal confluence or the superior mesenteric vein. Significant vascular encasement, nodal metastases, and liver metastases are also well depicted at CT, and these patients are usually deemed unresectable.